pathogenic acanthamoeba t4 genotype isolated from mucosal tissue of a patient with hiv infection: a case report
نویسندگان
چکیده
opportunistic infections due to free-living amoebae such as granulomatous amoebic encephalitis (gae), cutaneous acanthamoebiasis and disseminated infections could be the causative agent of mortality in people living with hiv/aids. in this study, we report the occurrence of the acanthamoeba belonging to the t4 genotype isolated from nasal and oral swabs of a 15 -yr-old man with hiv infection. hiv was confirmed using elisa kit and rt-pcr assay. the isolated strain showed pathogenic potential using thermo and osmotolerance assays. this patient might be vulnerable to develop gae or disseminated infections and depending on the immunologic status of the patient, this could be a health threat. monitoring of such patients, appropriate diagnostic procedures and improved-hiv related care can alter the outcome of such infections.
منابع مشابه
Pathogenic Acanthamoeba T4 Genotype Isolated from Mucosal Tissue of a Patient with HIV Infection: A Case Report
Opportunistic infections due to free-living amoebae such as Granulomatous Amoebic Encephalitis (GAE), cutaneous acanthamoebiasis and disseminated infections could be the causative agent of mortality in people living with HIV/AIDS. In this study, we report the occurrence of the Acanthamoeba belonging to the T4 genotype isolated from nasal and oral swabs of a 15-yr-old man with HIV infection. HIV...
متن کاملPotentially pathogenic Acanthamoeba genotype T4 isolated from dental units and emergency combination showers
BACKGROUND Acanthamoeba is the genus of free-living amoebae that is most frequently isolated in nature. To date, 20 Acanthamoeba genotypes have been described. Genotype T4 is responsible for approximately 90% of encephalitis and keratitis cases. Due to the ubiquitous presence of amoebae, isolation from environmental sources is not uncommon; to determine the clinical importance of an isolation, ...
متن کاملPathogenic Assays of Acanthamoeba Belonging to the T4 Genotype
BACKGROUND Acanthamoeba genus is introduced as opportunistic and cosmopolitan parasite. Monkey and wistar rat are appropriate models for experimental study on Acanthamoeba infection. In this study Acanthamoeba spp. were isolated from hot spring (HS), windows dust (WD) and a corneal sample of keratitis patient (KP) and their pathogenicity surveyed by in vitro and in vivo tests. METHODS Isolate...
متن کاملpathogenic assays of acanthamoeba belonging to the t4 genotype.
background: acanthamoeba genus is introduced as opportunistic and cosmopoli-tan parasite. monkey and wistar rat are appropriate models for experimental study on acanthamoeba infection. in this study acanthamoeba spp. were isolated from hot spring (hs), windows dust (wd) and a corneal sample of keratitis patient (kp) and their pathogenicity surveyed by in vitro and in vivo tests. methods: isolat...
متن کاملIn vitro activity of Trigonella foenum graecum seeds against a clinical strain of Acanthamoeba genotype T4
Acanthamoeba keratitis (AK) is a sight-threatening infection of the cornea disease that often presents with a lengthy and not fully effective treatment. Current therapeutic options against Acanthamoeba are not very effective against the cyst. Calibrated trophozoite/cyst suspension was incubated with the same volume of serial dilutions of the Trigonella foenum graecum aqueous extract (200, 250, ...
متن کاملIn vitro activity of Trigonella foenum graecum seeds against a clinical strain of Acanthamoeba genotype T4
Acanthamoeba keratitis (AK) is a sight-threatening infection of the cornea disease that often presents with a lengthy and not fully effective treatment. Current therapeutic options against Acanthamoeba are not very effective against the cyst. Calibrated trophozoite/cyst suspension was incubated with the same volume of serial dilutions of the Trigonella foenum graecum aqueous extract (200, 250, ...
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عنوان ژورنال:
iranian journal of parasitologyجلد ۱۲، شماره ۱، صفحات ۱۴۳-۱۴۷
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